| Renal cell carcinoma: correlation of CT findings with nuclear morphologic grading in 100 tumors. | |
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MedLine Citation:
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PMID: 8019359 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The contrast-enhanced preoperative computed tomographic (CT) scans and microscopic slides of 94 patients with 100 surgically resected renal cell carcinomas (RCCs) were retrospectively and independently reviewed in order to correlate the CT imaging findings of RCC with nuclear grading. As nuclear grade increased, RCCs were more likely to be of higher stage and greater size at presentation, and appeared more heterogeneous and less marginated. Of the features analyzed, tumor margination most closely correlated with nuclear grade. Overlap in the CT appearance of individual tumors limited the potential of CT to differentiate RCCs of varying grade. Small, well-marginated, homogeneous tumors, however, were either grade I or II, and were distinguishable from the more aggressive grade III lesions, which generally displayed irregular margins and greater inhomogeneity. |
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Authors:
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B A Birnbaum; M A Bosniak; G A Krinsky; D Cheng; J Waisman; M M Ambrosino |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Abdominal imaging Volume: 19 ISSN: 0942-8925 ISO Abbreviation: Abdom Imaging Publication Date: 1994 May-Jun |
Date Detail:
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Created Date: 1994-07-29 Completed Date: 1994-07-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9303672 Medline TA: Abdom Imaging Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 262-6 Citation Subset: IM |
Affiliation:
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Department of Radiology, New York University Medical Center, NY 10016. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Carcinoma, Renal Cell / pathology*, radiography* Cell Nucleus / ultrastructure Female Humans Kidney Neoplasms / pathology*, radiography* Male Middle Aged Neoplasm Staging Tomography, X-Ray Computed* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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