| Renal biopsy in type 2 diabetes: timing of complications and evaluating of safety in Chinese patients. | |
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MedLine Citation:
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PMID: 21175985 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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AIM: It has been recognized that renal lesions in patients with diabetes often have other causes of renal damage concomitantly. Renal biopsy is a valuable tool to provide histological evidence. However, the safety in patients with type 2 diabetes receiving renal biopsy is not well evaluated. This study was conducted to monitor the dynamic complications and to evaluate the safety of biopsy in diabetic patients. METHODS: A prospective observation was performed on 130 patients with type 2 diabetes and 150 patients not undergoing renal biopsy. The complications were monitored at 4 h, 8 h, 24 h, 48 h and 72 h sequentially after biopsy. RESULTS: Haematoma was observed in 34 (26.15%) patients with diabetes and 50 (33.33%) in controls (P=0.19). The timing of large haematoma peaked at 4 h. Gross haematuria occurred in 12 (9.23%) diabetic patients and eight (5.33%) controls (P=0.207). It happened mainly within 8 h. Renal pathological diagnosis showed 96 (73.85%) cases with diabetic nephropathy and 34 (26.15%) cases with non-diabetic renal disease. CONCLUSION: Renal biopsy in patients with type 2 diabetes is safe. The frequency of complications after renal biopsy in diabetes is no higher than those without diabetes. The complications mostly happened within 8 h, especially within 4 h. Biopsy is also very necessary to rule out other chronic renal diseases in diabetes. |
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Authors:
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Pei-Pei Zhang; Yong-Chun Ge; Shi-Jun Li; Hong-Lang Xie; Lei-Shi Li; Zhi-Hong Liu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nephrology (Carlton, Vic.) Volume: 16 ISSN: 1440-1797 ISO Abbreviation: Nephrology (Carlton) Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9615568 Medline TA: Nephrology (Carlton) Country: Australia |
Other Details:
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Languages: eng Pagination: 100-5 Citation Subset: IM |
Copyright Information:
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© 2011 The Authors. Nephrology © 2011 Asian Pacific Society of Nephrology. |
Affiliation:
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Research Institute of Nephrology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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