Document Detail


Renal autotransplantation--a possibility in the treatment of complex renal vascular diseases and ureteric injuries.
MedLine Citation:
PMID:  23274320     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: We report our contemporary experiences with renal autotransplantation in patients with complicated renal vascular diseases and/or complex ureteral injuries. Since its first performance, renal autotransplantation has been steadily improved and become a safe and effective procedure.
MATERIAL/METHODS: Between 1998 and 2006, 6 renal autotransplantations in 6 patients were performed at the University Medical Center of Leipzig. After nephrectomy and renal perfusion ex vivo, the kidney was implanted standardized in the fossa iliaca. The vessels were anastomized to the iliac vessels, the ureter was reimplanted in an extravesical tunneled ureteroneocystostomy technique according to Lich-Gregoir. Demographic, clinical, and laboratory data of the patients were collected and analyzed for pre-, intra-, and postoperative period.
RESULTS: Indications for renal autotransplantation were complex renovascular diseases in 2 patients (1 with fibromuscular dysplasia and 1 with Takayasu's arteritis) and in 4 patients with complex ureteral injuries. The median duration of follow-up was 9.7 years (range: 5.6-13.3). The laboratory values of our 6 patients showed improvements of creatinine, urea and blood pressure levels in comparison to the preoperative status at the end of follow-up period.
CONCLUSIONS: The present study reports excellent results of renal autotransplantation in patients with renovascular disease or complex ureteric injuries. After a median follow-up of 9.7 years all 6 patients present with stable renal function as well as normal blood pressure values. Postoperative complications were observed with a rate comparable to other studies.
Authors:
Hans Michael Hau; Michael Bartels; Hans-Michael Tautenhahn; Mehmet Haluk Morgul; Peter Fellmer; Phuc Ho-Thi; Christoph Benckert; Dirk Uhlmann; Michael Moche; Armin Thelen; Moritz Schmelzle; Sven Jonas
Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Annals of transplantation : quarterly of the Polish Transplantation Society     Volume:  17     ISSN:  2329-0358     ISO Abbreviation:  Ann. Transplant.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-31     Completed Date:  2013-05-28     Revised Date:  2013-06-17    
Medline Journal Info:
Nlm Unique ID:  9802544     Medline TA:  Ann Transplant     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  21-7     Citation Subset:  IM    
Affiliation:
Department of Visceral, Transplantation, Vascular and Thoracic Surgery, University Hospital of Leipzig, Liebigstrasse 20, Leipzig, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Female
Fibromuscular Dysplasia / surgery*
Follow-Up Studies
Humans
Kidney Transplantation / methods*
Male
Middle Aged
Nephrectomy
Postoperative Complications / epidemiology
Recovery of Function
Takayasu Arteritis / surgery*
Transplantation, Autologous
Treatment Outcome
Ureter / injuries*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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