Document Detail

Renal artery stenosis after renal transplantation: the impact of the hypogastric artery anastomosis.
MedLine Citation:
PMID:  8483249     Owner:  NLM     Status:  MEDLINE    
A review of 402 renal allotransplants performed during a 5-year period revealed 25 cases of transplant renal artery stenosis in 377 evaluable patients. To our knowledge this is the first large study of this transplant complication in which all patients received cyclosporine immunotherapy. The incidence of transplant renal artery stenosis was 6.6%. The mean internal from transplantation to onset of transplant renal artery stenosis was 11 months. No significant differences in atherosclerotic risk factors were detected between the groups with and without transplant renal artery stenosis. The incidence of acute allograft rejection was not increased in the stenosis group. There was no difference in the incidence of transplant renal artery stenosis following end-to-end (hypogastric artery) or end-to-side (common or external iliac artery) arterial anastomoses. Among patients having end-to-end hypogastric artery anastomoses the incidence of transplant renal artery stenosis was significantly greater (p < 0.01) when endarterectomy was required to render the hypogastric artery suitable for use. Percutaneous transluminal angioplasty was performed in 20 patients and open repair was performed in 18. After percutaneous transluminal angioplasty of hypogastric artery anastomoses, more additional procedures were required and there was a higher allograft loss rate when compared to percutaneous transluminal angioplasty of the external iliac artery. These data suggest that treatment of transplant renal artery stenosis in patients with end-to-end hypogastric artery anastomosis is more difficult and results in a higher morbidity rate than treatment in the external iliac artery group.
R S Sutherland; E K Spees; J W Jones; D W Fink
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  149     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1993 May 
Date Detail:
Created Date:  1993-05-28     Completed Date:  1993-05-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  980-5     Citation Subset:  AIM; IM    
Department of Surgery, Fitzsimons Army Medical Center, Aurora, Colorado.
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MeSH Terms
Anastomosis, Surgical / methods
Angioplasty, Balloon
Iliac Artery / surgery*
Kidney Transplantation*
Middle Aged
Postoperative Complications*
Renal Artery Obstruction / etiology*,  radiography,  therapy
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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