Document Detail

Renal Function Is Impaired in Small for Gestational Age Premature Infants.
MedLine Citation:
PMID:  23035924     Owner:  NLM     Status:  Publisher    
Abstract Objectives: Small for gestational age (SGA) premature infants are at increased risk for complications. We aimed to evaluate if SGA infants are at higher risk for presenting renal insufficiency in the newborn period compared to appropriate for gestational age (AGA) premature infants. Methods: We conducted a retrospective case-control study of infants ≤ 34 weeks gestation. Markers of renal function based upon the Acute Kidney Injury Network were compared between both groups. Results: Twenty SGA infants were compared to twenty AGA infants matching in sex and gestational age. SGA infants had higher serum creatinine on day of life (DOL) 1 (p= 0.014) and DOL 3 (p=0.05) and a higher overall maximum creatinine concentration (p=0.013). They were also more likely to have an increase in serum creatinine more than 0.3 mg/dl in a 48-hour period (OR: 7.8, p= 0.008) and increase in serum creatinine more than 50% in a 48-hour period (OR: 12.4, p=0.002). Urine output (ml/kg/hr) was significantly less in the SGA group on DOL 3 (p= 0.002) and DOL 7 (p= 0.017). Conclusions: SGA infants are at increased risk for renal insufficiency during the neonatal period, thereby implying the need for special considerations in their fluid and medication management.
Jonathan Davies; Mohamed El-Dib; An Massaro; Hany Aly
Related Documents :
23429454 - Serum cytosolic β-glucosidase levels in neonatal necrotizing enterocolitis.
16444384 - The role of serum and urinary urea in the evaluation of enteral protein intake in adequ...
22928654 - Probiotics to improve outcomes of colic in the community: protocol for the baby biotics...
24556944 - Early detection of prenatal cardiocirculatory compromise in small for gestational age i...
16610484 - Car seat safety for high-risk infants.
23016614 - Oxygen administration for the resuscitation of term and preterm infants.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-4
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Departments of Pediatrics, Washington, DC, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The use of daily aspirin, nutritional supplements and alternative medications among Amish and non-Am...
Next Document:  Load emphasizes muscle effort minimization during selection of arm movement direction.