| Renal denervation for hypertension. | |
| | |
MedLine Citation:
|
PMID: 22440489 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Systemic hypertension is a major burden to the individual and society. Its association with major adverse cardiac and cerebral events and favorable effects of antihypertensive therapy are undisputed. However, despite multidrug therapy, blood pressures are frequently suboptimally controlled. Moreover, adverse drug effects often interfere with patients' lifestyles and affect compliance. Therefore, alternative treatment strategies have been explored. Most recently, attention has been redirected to the sympathetic nervous system (SNS) in the pathogenesis of hypertension. In addition, interruption of the renal SNS in humans with resistant hypertension has been studied with promising results. The following review provides an overview of the anatomy and physiology of the renal SNS, the rational for manipulating the SNS, and the results of therapeutic renal sympathetic denervation. |
| | |
Authors:
|
Stefan C Bertog; Paul A Sobotka; Horst Sievert |
Related Documents
:
|
962259 - Possibility of isoproterenol therapy with soft contact lenses: ocular hypotension witho... 19920669 - Rapid visual recovery and long-term intraocular pressure control after donor scleral pa... 2750839 - Low intraocular pressure and postural changes in intraocular pressure in patients with ... 3676739 - Time course of degeneration of the visual system induced by spontaneous glaucoma in the... 1004809 - Rotoextractor evacuation of total hyphema. 12470969 - Modifying subsceral fluid pressure in an experimental model of mitomycin-c diffusion. 7313299 - Myocardial mitochondrial synthesis in response to various workloads. 2419699 - Acute hemodynamic effects of piroximone (mdl 19,205) in patients with moderate congesti... 1501059 - Seasonal incidence of eclampsia and its relationship to meteorological data in mozambique. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: JACC. Cardiovascular interventions Volume: 5 ISSN: 1876-7605 ISO Abbreviation: JACC Cardiovasc Interv Publication Date: 2012 Mar |
Date Detail:
|
Created Date: 2012-03-23 Completed Date: 2012-07-24 Revised Date: 2012-08-29 |
Medline Journal Info:
|
Nlm Unique ID: 101467004 Medline TA: JACC Cardiovasc Interv Country: United States |
Other Details:
|
Languages: eng Pagination: 249-58 Citation Subset: IM |
Copyright Information:
|
Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. |
Affiliation:
|
Cardiovascular Center Frankfurt, Frankfurt, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Blood Pressure* Catheter Ablation Humans Hypertension / physiopathology, surgery* Kidney / innervation* Sympathectomy* / methods Sympathetic Nervous System / physiopathology, surgery* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ibuprofen Prevents Altitude Illness: A Randomized Controlled Trial for Prevention of Altitude Illnes...
Next Document: Different prognostic significance of high on-treatment platelet reactivity as assessed by the Verify...