Document Detail

Renal Consequences of Intraabdominal Hypertension in a Porcine Model. Search for the Choice Indirect Technique for Intraabdominal Pressure Measurement.
MedLine Citation:
PMID:  23122948     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To study the effects on the renal system in a porcine model of intraabdominal hypertension, and to determine the indirect technique of choice for determination of the intraabdominal pressure. MATERIAL AND METHODS: 30 pigs were used divided in two groups according with increased intraabdominal pressure values (20mmHg and 30mmHg). In both groups pressures were registered 8 times, summing up to 3hours, with a CO(2) insufflator. Three different measures of the intraabdominal pressure were taken: a direct transperitoneal measure, using a catheter of Jackson-Pratt connected to a pressure transducer, and two indirect measures, a transvesical by means of a Foley to manometer system, and a transgastric by introducing in the stomach a catheter connected to a pressure monitor with electronic hardware. Mean arterial pressure was calculated, along with the cardiac index, production of urine and serum creatinine. RESULTS: There was a greater correlation between the transvesical and the transperitoneal intraabdominal pressures (R(2)=0,95). Average transgastric intraabdominal pressure was inferior to the transperitoneal indicator in all taken measurements. The average arterial pressure descended in both groups, with earlier significant differences observed at 30mmHg (p<0,020). Urine production was lower at 30mmHg compared with the 20mmHg group (9,63±1,57 versus 3.26 ml±1,73). Serum creatinine increased in both groups being pathological at 30mmHg after 1h 20min, with existing differences between early pressures (p<0,027). CONCLUSIONS: This study revealed marked renal affectation with higher severity at 30mmHg pressures. The transvesical technique showed a greater correlation with the direct measurement technique used, defining this as the method of choice for determination of intraabdominal pressure.
L Correa-Martín; G Castellanos; M García; F M Sánchez-Margallo
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-31
Journal Detail:
Title:  Actas urologicas espanolas     Volume:  -     ISSN:  1699-7980     ISO Abbreviation:  Actas Urol Esp     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-11-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7704993     Medline TA:  Actas Urol Esp     Country:  -    
Other Details:
Languages:  ENG; SPA     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 AEU. Published by Elsevier Espana. All rights reserved.
Unidad de Laparoscopia, Centro de Cirugía de Mínima Invasión Jesús Usón, Cáceres, España. Electronic address:
Vernacular Title:
Consecuencias renales de la hipertensión intraabdominal en modelo porcino. Búsqueda de la técnica indirecta de elección de la medida de la presión intraabdominal.
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