| Remyelination in multiple sclerosis. | |
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MedLine Citation:
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PMID: 12559508 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Remyelination in multiple sclerosis (MS) lesions has been described in several studies. It depends on the presence of myelinating oligodendrocytes and a functional interaction between these myelinating cells and axons. The imaging signal of remyelination in magnetic resonance imaging or spectroscopy is not yet defined. The present review will focus on the morphological appearance of remyelinating MS lesions, their correlation with oligodendrocyte pathology, and possible markers for remyelination in imaging. |
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Authors:
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Wolfgang Brück; Tanja Kuhlmann; Christine Stadelmann |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Journal of the neurological sciences Volume: 206 ISSN: 0022-510X ISO Abbreviation: J. Neurol. Sci. Publication Date: 2003 Feb |
Date Detail:
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Created Date: 2003-01-31 Completed Date: 2003-04-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: Netherlands |
Other Details:
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Languages: eng Pagination: 181-5 Citation Subset: IM |
Affiliation:
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Institut für Neuropathologie, Charité, Campus Virchow-Klinikum, Humboldt-Universität, Augustenburger Platz 1, 13353, Berlin, Germany. wolfgang.brueck@charite.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Axons / pathology Central Nervous System / pathology, physiopathology Humans Magnetic Resonance Imaging / methods Multiple Sclerosis / physiopathology*, therapy Myelin Sheath / pathology Oligodendroglia / pathology Rats Regeneration |
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