| Removal of cetyltrimethylammonium bromide to enhance the biocompatibility of Au nanorods synthesized by a modified seed mediated growth process. | |
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MedLine Citation:
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PMID: 19049082 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Previously, we reported the synthesis of stable gold nanorods with higher aspect ratio (approximately 15-20) and more enhanced uniformity by a modified seed mediated growth approach using a binary surfactant system consisting of CTAB and Pluronic F-127. For the in vivo application of gold nanorods, the removal of CTABs that are strongly bound on prepared Au nanorods is necessary due to their cytotoxicity. Use of heat or acid at various conditions was performed to achieve the complete removal of CTAB from the synthesized Au nanorods while maintaining their stability. Here, we report the appropriate conditions for both treatments that can remove CTAB efficiently without hampering the stability of Au nanorods. After the removal of CTAB, Pluronic F-127 was added additionally for the stabilization and further potential functionalization of Au nanorods to make useful for various applications. VIS-NIR absorption spectroscopy, SEM, TEM, and FTIR were used for characterization. |
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Authors:
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Byung-Sang Choi; Muhammad Iqbal; Takhee Lee; Young Ha Kim; Giyoong Tae |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of nanoscience and nanotechnology Volume: 8 ISSN: 1533-4880 ISO Abbreviation: J Nanosci Nanotechnol Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-12-03 Completed Date: 2008-12-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101088195 Medline TA: J Nanosci Nanotechnol Country: United States |
Other Details:
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Languages: eng Pagination: 4670-4 Citation Subset: IM |
Affiliation:
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Research Center for Biomolecular Nanotechnology, Department of Materials Science and Engineering, Gwangju Institute of Science and Technology, Gwangju 500-712, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biocompatible Materials
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chemistry* Cetrimonium Compounds / chemistry* Crystallization Gold / chemistry* Metal Nanoparticles / chemistry Microscopy, Electron, Scanning Microscopy, Electron, Transmission Nanostructures / chemistry Nanotechnology / methods Nanotubes / chemistry Poloxamer / chemistry Spectroscopy, Fourier Transform Infrared Spectroscopy, Near-Infrared Temperature |
| Chemical | |
Reg. No./Substance:
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0/Biocompatible Materials; 0/Cetrimonium Compounds; 106392-12-5/Poloxamer; 6899-10-1/cetrimonium; 7440-57-5/Gold |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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