| Removal of cartilage rings of the graft and omentopexy for extended tracheal autotransplantation. | |
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MedLine Citation:
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PMID: 10215227 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: One of the serious problems in longer-size tracheal transplantation is infection or severe stenosis of the graft, probably caused by an inadequate blood supply even with omentopexy. For obtaining an appropriate blood supply, we experimentally developed a new technique that included removal of some cartilage rings of the graft and omentopexy. METHODS: Twenty-one adult mongrel dogs were used. In group A (n = 11), a nine-cartilage ring length of the trachea in which six of nine rings were removed, leaving one cartilage ring at each end of the graft and another in the center, was autotransplanted with omentopexy. Two artificial tracheal rings outside the graft were used for maintaining the lumen. In group B (n = 10), a nine-cartilage ring length of the trachea was autotransplanted with omentopexy. RESULTS: In group A, all dogs survived until being sacrificed, whereas 5 group B dogs died of graft infection and mediastinitis (p<0.05 versus group A). Mucosal blood flow of the graft in group A was normal and higher than in group B (p<0.05). Grade of the graft stenosis at death or sacrifice was 14%+/-1% in group A and 58%+/-25% in group B (p<0.05). CONCLUSIONS: Removal of some cartilage rings improved blood supply to the graft and resulted in satisfactory survival and nonsignificant tracheal stenosis in extended tracheal autotransplantation. |
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Authors:
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K Murai; H Oizumi; T Masaoka; T Fujishima; M Abiko; S Shiono; Y Shimazaki |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 67 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 1999 Mar |
Date Detail:
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Created Date: 1999-05-06 Completed Date: 1999-05-06 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 776-80 Citation Subset: AIM; IM |
Affiliation:
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Second Department of Surgery, Yamagata University School of Medicine, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bronchoscopy Cartilage / surgery Dogs Implants, Experimental Mucous Membrane / blood supply, pathology Omentum / surgery Surgical Flaps / blood supply* Trachea / blood supply, pathology, transplantation* Tracheal Stenosis / etiology Transplantation, Autologous / adverse effects, methods |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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