Document Detail

Remote effects of acute ischemic stroke: A xenon CT cerebral blood flow study.
MedLine Citation:
PMID:  10773649     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to verify transhemispheric diaschisis in the early hours after an ischemic event. METHODS: XeCT cerebral blood flow (CBF) studies within 8 h of stroke were studied in 23 patients. Mean CBF was evaluated in the ischemic area, contralateral hemisphere and ipsilateral cerebellum. RESULTS: A severe CBF reduction was found in the ischemic area (mean 9 +/- 3 ml/100 g/min). The mean CBF in the unaffected hemisphere (33 +/- 10 ml/100 g/min) was 35% less compared to the normal mean value. CBF was decreased in the cerebellum ipsilateral to the stroke (mean 31 +/- 12 ml/100 g/min) suggesting a blood flow depression of the whole brain. CONCLUSIONS: During the initial hours of cerebral ischemia, the asymptomatic hemisphere demonstrated CBF depression that was part of the global flow reduction.
G Rubin; E I Levy; A M Scarrow; A D Firlik; A Karakus; L Wechsler; C A Jungreis; H Yonas
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cerebrovascular diseases (Basel, Switzerland)     Volume:  10     ISSN:  1015-9770     ISO Abbreviation:  Cerebrovasc. Dis.     Publication Date:    2000 May-Jun
Date Detail:
Created Date:  2000-06-30     Completed Date:  2000-06-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9100851     Medline TA:  Cerebrovasc Dis     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  221-8     Citation Subset:  IM    
Copyright Information:
Copyright 2000 S. Karger AG, Basel.
Department of Neurosurgery, University of Pittsburgh, Pittsburgh, PA, USA.
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MeSH Terms
Aged, 80 and over
Anterior Cerebral Artery / radiography
Brain / blood supply*
Brain Ischemia / physiopathology*,  radiography
Cerebrovascular Circulation*
Functional Laterality
Middle Aged
Middle Cerebral Artery / radiography
Regional Blood Flow
Stroke / physiopathology*,  radiography
Tomography, X-Ray Computed*
Reg. No./Substance:

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