Document Detail


Remnants of occipital vertebrae: proatlas segmentation abnormalities.
MedLine Citation:
PMID:  19404154     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Developmental remnants around the foramen magnum, or proatlas segmentation abnormalities, have been recorded in postmortem studies but very rarely in a clinical setting. Because of their rarity, the pathological anatomy has been misunderstood, and treatment has been fraught with failures. The objectives of this prospective study were to understand the correlative anatomy, pathology, and embryology and to recognize the clinical presentation and gain insights on the treatment and management. METHODS: Our craniovertebral junction (CVJ) database started in 1977 and comprises 5200 cases. This prospective study has retrieval capabilities. Neurodiagnostic studies changed with the evolution of imaging. Seventy-two patients were recognized as having symptomatic proatlas segmentation abnormalities. RESULTS: Ventral bony masses from the clivus or medial occipital condyle occurred in 66% (44/72), lateral or anterolateral compressive masses in 37% (27 of 72 patients), and dorsal bony compression in 17% (12 of 72 patients). Hindbrain herniation was associated in 33%. The age at presentation was 3 to 23 years. Motor symptoms occurred in 72% (52 of 72 patients); palsies in Cranial Nerves IX, X, and XII in 33% (24 of 72 patients); and vertebrobasilar symptoms in 25% (18 of 72 patients). Trauma precipitated symptoms in 55% (40 of 72 patients). The best definition of the abnormality was demonstrated by 3-dimensional computed tomography combined with magnetic resonance imaging. Treatment was aimed at decompression of the pathology and stabilization. CONCLUSION: Remnants of the occipital vertebrae around the foramen magnum were recognized in 72 of 5200 CVJ cases (7.2%). Magnetic resonance imaging with 3-dimensional computed tomography of the CVJ provides the best definition and understanding of the lesions. Brainstem myelopathy and lower cranial nerve deficits are common clinical presentations in the first and second decades of life. Treatment is aimed at decompression of the pathology and CVJ stabilization.
Authors:
Arnold H Menezes; Kathleen A Fenoy
Related Documents :
13679284 - Mr imaging of traumatic lesions of the inferior alveolar nerve in patients with fractur...
1621924 - Neurological impairment in congenital bilateral ptosis with ophthalmoplegia.
1658094 - Curved ct reformatted images of head scans.
2342804 - Gadolinium-dtpa-enhanced magnetic resonance imaging in optic neuropathies.
10072644 - Contribution of tridimensional sonography and magnetic resonance imaging to prenatal di...
18535874 - Dual-time-point fdg-pet for evaluation of lymph node metastasis in patients with non-sm...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurosurgery     Volume:  64     ISSN:  1524-4040     ISO Abbreviation:  Neurosurgery     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-30     Completed Date:  2009-07-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802914     Medline TA:  Neurosurgery     Country:  United States    
Other Details:
Languages:  eng     Pagination:  945-53; discussion 954     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA. arnold-menezes@uiowa.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Atlanto-Axial Joint / pathology*
Cervical Atlas / pathology*
Child
Child, Preschool
Female
Foramen Magnum / pathology*
Humans
Imaging, Three-Dimensional / methods
Magnetic Resonance Imaging / methods
Male
Occipital Bone / pathology*
Prospective Studies
Retrospective Studies
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Surgical treatment of cerebellar schistosomiasis.
Next Document:  Radiographic restoration of lumbar alignment after transforaminal lumbar interbody fusion.