| Remission of relapsing childhood nephrotic syndrome with mycophenolate mofetil. | |
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MedLine Citation:
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PMID: 10752763 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a 21-year-old male with childhood-onset familial nephrotic syndrome and frequent relapses who manifested toxicity or treatment resistance to corticosteroids, cyclophosphamide, cyclosporin-A, and tacrolimus. Monotherapy with mycophenolate mofetil (MMF) resulted in maintenance of clinical remission for 14 months without noticeable toxicity, while allowing resolution of steroid-induced side effects. Our observation suggests that MMF may be useful in maintaining remission in nephrotic patients who manifest toxicity to standard immunosuppressive agents. |
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Authors:
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M Chandra; M Susin; C Abitbol |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric nephrology (Berlin, Germany) Volume: 14 ISSN: 0931-041X ISO Abbreviation: Pediatr. Nephrol. Publication Date: 2000 Mar |
Date Detail:
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Created Date: 2000-05-09 Completed Date: 2000-05-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8708728 Medline TA: Pediatr Nephrol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 224-6 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, North Shore University Hospital, New York University School of Medicine, Manhasset 11030, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Child, Preschool Drug Resistance Humans Immunosuppressive Agents / adverse effects, therapeutic use* Male Mycophenolic Acid / analogs & derivatives*, therapeutic use Nephrotic Syndrome / drug therapy* Recurrence Remission Induction Retreatment |
| Chemical | |
Reg. No./Substance:
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0/Immunosuppressive Agents; 128794-94-5/mycophenolate mofetil; 24280-93-1/Mycophenolic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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