Document Detail


Remission of myasthenia gravis caused by proteinuria in nephrotic syndrome.
MedLine Citation:
PMID:  9390672     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Myasthenia gravis is caused by antibodies against acetylcholine receptors and is treated with inhibition or elimination of antibody production. We report a 43-year-old myasthenic female who was symptomatic until she developed proteinuria from nephrotic syndrome, which caused a marked drop in acetylcholine receptor antibody titer with remission of myasthenia. Treatment of the nephrotic syndrome produced exacerbation of her myasthenia and a rise in antibody level. This patient's improvement is the result of antibody elimination during proteinuria in nephrotic syndrome.
Authors:
M Almsaddi; T E Bertorini; W Bastnagel
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Muscle & nerve     Volume:  20     ISSN:  0148-639X     ISO Abbreviation:  Muscle Nerve     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1997-12-23     Completed Date:  1997-12-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7803146     Medline TA:  Muscle Nerve     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1583-6     Citation Subset:  IM    
Affiliation:
Department of Neurology, University of Tennessee Memphis, 38163, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antibodies / analysis
Female
Humans
Myasthenia Gravis / complications*,  immunology,  physiopathology*
Nephrotic Syndrome / complications*,  urine*
Proteinuria / etiology*,  physiopathology*
Receptors, Cholinergic / immunology
Remission, Spontaneous
Chemical
Reg. No./Substance:
0/Antibodies; 0/Receptors, Cholinergic

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