Document Detail


Remission in juvenile idiopathic arthritis.
MedLine Citation:
PMID:  17083772     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Until recently, no uniform and widely accepted criteria for defining remission in juvenile idiopathic arthritis (JIA) were available. In recent years, a set of preliminary criteria for clinical remission in JIA was developed through an international collaborative effort. These criteria enable the classification of patients in the states of inactive disease, clinical remission with medication, and clinical remission without medication. The first phase of the validation process of the criteria, which was accomplished recently, established that they are feasible and have good face, content and construct validity, and strong discriminant properties. A few studies have applied the new remission criteria in series of patients with JIA, with results that concur with those of previous surveys in showing that only a few patients with JIA have a chance of remaining in long-term remission status without medications. These findings highlight the critical need for therapies that have the capacity to induce sustained complete disease control of JIA.
Authors:
A Ravelli; A Martini
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical and experimental rheumatology     Volume:  24     ISSN:  0392-856X     ISO Abbreviation:  Clin. Exp. Rheumatol.     Publication Date:    2006 Nov-Dec
Date Detail:
Created Date:  2006-11-06     Completed Date:  2007-05-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8308521     Medline TA:  Clin Exp Rheumatol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  S105-10     Citation Subset:  IM    
Affiliation:
Dirigente Medico, Pediatria II, Istituto di Ricovero e Cura a Carattere Scientifico G. Gaslini, Genova, Italy. angeloravelli@ospedale-gaslini.ge.it
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MeSH Terms
Descriptor/Qualifier:
Arthritis, Juvenile Rheumatoid / immunology*,  pathology,  therapy
Clinical Trials as Topic
Endpoint Determination*
Humans
Inflammation / drug therapy,  physiopathology
Remission Induction
Severity of Illness Index*
Survivors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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