Document Detail

Remifentanil for conscious sedation and analgesia during awake fiberoptic tracheal intubation: a case report with pharmacokinetic simulations.
MedLine Citation:
PMID:  10396721     Owner:  NLM     Status:  MEDLINE    
We report a case of awake, fiberoptic tracheal intubation of a difficult airway (Ludwig's angina) using remifentanil as part of the sedation-analgesia regimen. Remifentanil's rapid onset-rapid offset pharmacokinetic profile enabled precise control of the level of opioid effect. In combination with other drugs, remifentanil may offer some clinical advantages compared to the other fentanyl congeners in providing the opioid component of conscious sedation-analgesia for awake tracheal intubation in patients with difficult airways.
M D Reusche; T D Egan
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical anesthesia     Volume:  11     ISSN:  0952-8180     ISO Abbreviation:  J Clin Anesth     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-09-14     Completed Date:  1999-09-14     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8812166     Medline TA:  J Clin Anesth     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  64-8     Citation Subset:  IM    
Department of Anesthesiology, University of Utah School of Medicine, Salt Lake City 84132, USA.
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MeSH Terms
Analgesics, Opioid / pharmacokinetics,  therapeutic use*
Computer Simulation*
Fiber Optic Technology*
Hypnotics and Sedatives / pharmacokinetics,  therapeutic use*
Intubation, Intratracheal
Piperidines / pharmacokinetics,  therapeutic use*
Tomography, X-Ray Computed
Reg. No./Substance:
0/Analgesics, Opioid; 0/Hypnotics and Sedatives; 0/Piperidines; 132875-61-7/remifentanil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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