Document Detail


Remember to consider dermatophyte infection when dealing with recalcitrant dermatoses.
MedLine Citation:
PMID:  9563426     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Superficial fungal infections of the skin are among the most common infections encountered in medicine. The diagnosis is easily confirmed with simple office-based procedures. In certain clinical situations, the diagnosis can be elusive. METHODS: We analyzed clinical data on five patients who came in referral for treatment of a recalcitrant dermatosis. RESULTS: All patients had their diagnosis confirmed by a positive potassium hydroxide preparation from skin scrapings or by a skin biopsy positive for fungal elements. All showed clinical improvement and ultimate resolution of their skin lesions with topical and/or systemic antifungal therapy. CONCLUSIONS: Diagnosis can be complicated by previous use of corticosteroid-containing topical and/or systemic agents, a clinical history closely resembling that of a photosensitive disorder, and a lack of clinical-histopathologic correlation. Laboratory procedures and skin biopsy of an ambiguous appearing lesion can be diagnostic, but an accurate diagnosis is dependent on communication between the clinician and the pathologist. We recommend that office-based procedures be done early in treatment so that subsequent efforts can be directed toward providing appropriate therapies.
Authors:
A G Abraham; C L Kulp-Shorten; J P Callen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  91     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1998 Apr 
Date Detail:
Created Date:  1998-05-06     Completed Date:  1998-05-06     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  349-53     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, University of Louisville School of Medicine, KY, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Antifungal Agents / therapeutic use
Dermatomycoses / diagnosis*,  drug therapy,  pathology
Diagnostic Errors
Female
Griseofulvin / therapeutic use
Humans
Hydroxides / diagnostic use
Ketoconazole / therapeutic use
Male
Middle Aged
Potassium Compounds / diagnostic use
Skin Diseases / microbiology*
Chemical
Reg. No./Substance:
0/Antifungal Agents; 0/Hydroxides; 0/Potassium Compounds; 126-07-8/Griseofulvin; 1310-58-3/potassium hydroxide; 65277-42-1/Ketoconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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