Document Detail

Remarks on the diagnosis of Clonorchis sinensis infection.
MedLine Citation:
PMID:  6439228     Owner:  NLM     Status:  MEDLINE    
A number of techniques have been developed for the diagnosis of Clonorchis sinensis infection. Although the most reliable technique for this infection are the various stool examinations in the laboratory, practical problems such as difficulties of stool collection and mass examinations need more applicable methods for epidemiological studies. During past decades some serologic and immunologic methods such as intradermal skin test, gel-diffusion technique, complement fixation test, haemagglutination test, fluorescent antibody test and enzyme-linked immunosorbent assay (ELISA) have been introduced for the diagnosis of clonorchiasis in Korea, but satisfactory results have not been obtained especially in field work because of the lack of available purified antigen. From this viewpoint it is essential to undertake careful isolation and purification of specific antigens. Recently ELISA has been well established as a micro-system for mass survey. In spite of the complexity of its procedures in contrast to the skin test the results obtained explain its importance. In this paper available serologic and immunologic methods for the diagnosis of clonorchiasis used at the Institute of Tropical Medicine, Yonsei University, Seoul, are reviewed, and the results from skin test and ELISA are compared and discussed.
D Y Min
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Arzneimittel-Forschung     Volume:  34     ISSN:  0004-4172     ISO Abbreviation:  Arzneimittelforschung     Publication Date:  1984  
Date Detail:
Created Date:  1985-01-18     Completed Date:  1985-01-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372660     Medline TA:  Arzneimittelforschung     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  1153-6     Citation Subset:  IM    
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MeSH Terms
Antibody Specificity
Antigens, Helminth / analysis
Clonorchiasis / diagnosis*
Clonorchis sinensis / immunology
Cross Reactions
Enzyme-Linked Immunosorbent Assay
Fluorescent Antibody Technique
Parasite Egg Count
Skin Tests
Reg. No./Substance:
0/Antigens, Helminth

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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