| [Remarkable improvement of the hip joint lesion in a patient with rheumatoid arthritis by the treatment with anti-TNF-α agents]. | |
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MedLine Citation:
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PMID: 21048388 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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22-year old woman who was previously diagnosed as having juvenile idiopathic arthritis (JIA) was treated with anti-TNF-α agents. Her disease activity was assessed as Stage IV and Class III by Steinbrocker's classification and resistant to steroids and methotrexate. Initially clinical findings responded well to infliximab (IFX), but polyarthritis recurred 15 months after the start of the treatment, and IFX was switched to etanercept (ETN) with good response. On the other hand, effects on the osteoarticular lesions were continuously observed through the period of the treatment with these two biologics. It was thought very rare that weight-bearing joint like the hip joint was restored as was seen in this case, while its mechanism is unknown. Because mechanism for inhibition of inflammation or joint destruction might be independent, we should investigate further the relationship between inflammation and joint destruction in the future. |
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Authors:
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Yasuaki Nagare; Koji Kinoshita; Fumiaki Nishisaka; Masakatsu Saito; Tohgo Nonaka; Masanori Funauchi |
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Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology Volume: 33 ISSN: 1349-7413 ISO Abbreviation: Nihon Rinsho Meneki Gakkai Kaishi Publication Date: 2010 |
Date Detail:
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Created Date: 2010-11-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9505992 Medline TA: Nihon Rinsho Meneki Gakkai Kaishi Country: Japan |
Other Details:
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Languages: jpn Pagination: 272-6 Citation Subset: IM |
Affiliation:
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Division of Nephrology and Rheumatology, Department of Internal Medicine, Kinki University Faculty of Medicine, Japan. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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