Document Detail

Relief of postlaminectomy syndrome in selected patients by injection of autogenous cerebrospinal fluid.
MedLine Citation:
PMID:  6455748     Owner:  NLM     Status:  MEDLINE    
We have been using the differential spinal block to study patients referred to our Pain Clinic for treatment of their chronic pain syndromes. In a selected group of chronic-pain patients from whom cerebrospinal fluid (CSF) could not be obtained at the L4 or L5 interspace, administration of autogenous CSF obtained at a higher interspace gave immediate and complete but temporary pain relief. Endorphins were present in these autogenous CSF samples. These studies, indicating that CSF even from chronic-pain patients contains analgesic substances (possibly endorphins), may point to new treatment modalities for certain chronic back pain syndromes.
K S Mays; B E Miller; E E Codd; V J Aloyo; A L Ungar; W C North; W Byrne
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Spine     Volume:  6     ISSN:  0362-2436     ISO Abbreviation:  Spine     Publication Date:    1981 May-Jun
Date Detail:
Created Date:  1981-10-25     Completed Date:  1981-10-25     Revised Date:  2009-07-09    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  274-6     Citation Subset:  IM    
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MeSH Terms
Analgesia / methods*
Back Pain / cerebrospinal fluid,  therapy*
Cerebrospinal Fluid
Endorphins / physiology
Lumbar Vertebrae
Middle Aged
Postoperative Complications
Reg. No./Substance:

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