Document Detail

Relief of intractable posthypoxic myoclonus after administration of agomelatine.
MedLine Citation:
PMID:  22986800     Owner:  NLM     Status:  MEDLINE    
Chronic posthypoxic myoclonus is characterized by myoclonic jerks that are specifically triggered by action. It is a rare but devastating sequela of hypoxic encephalopathy. We report a 42-year-old female patient with treatment-resistant chronic posthypoxic myoclonus, which improved with administration of the drug agomelatine. We suggest that agomelatine could represent a useful therapeutic option in the treatment of chronic posthypoxic myoclonus.
Jesús González de la Aleja; Rosa Ana Saiz-Díaz; Pilar De la Peña
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical neuropharmacology     Volume:  35     ISSN:  1537-162X     ISO Abbreviation:  Clin Neuropharmacol     Publication Date:    2012 Sep-Oct
Date Detail:
Created Date:  2012-09-18     Completed Date:  2013-07-09     Revised Date:  2013-07-17    
Medline Journal Info:
Nlm Unique ID:  7607910     Medline TA:  Clin Neuropharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  258-9     Citation Subset:  IM    
Epilepsy Unit, Department of Neurology, Hospital 12 de Octubre, Madrid, Spain.
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MeSH Terms
Acetamides / pharmacology,  therapeutic use*
Hypoxia, Brain / complications,  diagnosis*,  drug therapy*
Melatonin / agonists*
Myoclonus / diagnosis*,  drug therapy*,  etiology
Reg. No./Substance:
0/Acetamides; 138112-76-2/S 20098; 73-31-4/Melatonin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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