Document Detail

Relief from pain localized to the lower back in early labour. A double blind trial of ketocaine, a new, highly effective, local, cutaneous analgesic (A 2358, Ane-Pad), and placebo.
MedLine Citation:
PMID:  6461973     Owner:  NLM     Status:  MEDLINE    
Pain localized to the lower back in the first stage of labour in 47 primiparous women was treated by epicutaneous application of ketocaine or placebo compresses. Twenty-three patients were treated with ketocaine compresses (Ane-Ped), and 24 patients with compresses soaked with isotonic saline. The pain relieving effect was almost the same in both treatment groups. Pain localized to the lower back was reduced in about 50% of the patients after one hour's application of ketocaine or placebo compresses. Supplementary analgesics had to be administered in about 60% of the patients in each group. No maternal or foetal systemic side effects related to the treatment were registered. Local erythema on the application area was only reported in the ketocaine group. The frequency of feeling of warmth during the application of compresses of ketocaine were high compared to the placebo group, 78% and 29% respectively.
M Permin; L Ipsen; M K Hansen; L Andersen; E Petersen; L Rosengreen; M S Søfensen; D Bank; B Steffensen; B Gustafsson
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Zeitschrift für Geburtshilfe und Perinatologie     Volume:  185     ISSN:  0300-967X     ISO Abbreviation:  Z Geburtshilfe Perinatol     Publication Date:  1981 Dec 
Date Detail:
Created Date:  1982-06-21     Completed Date:  1982-06-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0326205     Medline TA:  Z Geburtshilfe Perinatol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  360-3     Citation Subset:  IM    
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MeSH Terms
Anesthesia, Obstetrical*
Back Pain / drug therapy*,  etiology
Butyrophenones* / administration & dosage
Clinical Trials as Topic
Double-Blind Method
Labor, Obstetric*
Random Allocation
Reg. No./Substance:
0/Butyrophenones; 1092-46-2/ketocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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