Document Detail


Reliability and sensitivity of frozen-section pancreatic biopsy.
MedLine Citation:
PMID:  3970667     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A collaborative Veterans Administration and University of California, Davis Medical Center group of 586 patients with histologically proved pancreatic carcinoma was reviewed. During laparotomy, 159 patients underwent 251 frozen-section pancreatic biopsies with subsequent permanent section examination of the same tissue block. All 112 positive frozen-section diagnoses were corroborated on permanent sectioning. The 47 patients with false-negative biopsy specimens were equally divided between sampling and interpretation error. We conclude that in this group of 159 pancreatic cancer patients, 30% failed to be correctly diagnosed by intraoperative frozen-section biopsy. This failure was due to patient sampling and interpretation error in equal proportion. Interpretation error rates were not influenced by the type or number of biopsies. Patient sampling error is apparently reduced by repeated biopsy, and specimen sampling error occurred less frequently with wedge biopsy.
Authors:
R P Campanale; C F Frey; L R Farias; P L Twomey; J M Guernsey; R Keehn; G Higgins
Related Documents :
1799787 - A 5-year experience with 307 ct-guided renal biopsies: results and complications.
21248677 - Assessment of venous thrombus time of progression by gray-scale median analysis.
22850807 - Children and adolescents with ureteropelvic junction obstruction: is an additional void...
6152947 - Abnormal endometrial echoes: sonographic spectrum of endometrial pathology.
20663157 - Assessment of atrial septal defects in adults comparing cardiovascular magnetic resonan...
273077 - Diagnosis of pheochromocytoma during treatment of a mandibular fracture: report of case.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Archives of surgery (Chicago, Ill. : 1960)     Volume:  120     ISSN:  0004-0010     ISO Abbreviation:  Arch Surg     Publication Date:  1985 Mar 
Date Detail:
Created Date:  1985-03-21     Completed Date:  1985-03-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9716528     Medline TA:  Arch Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  283-8     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Biopsy / methods*
False Negative Reactions
Frozen Sections*
Humans
Intraoperative Period
Microtomy*
Pancreas / pathology*
Pancreatic Neoplasms / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Splenic phagocytic function after partial splenectomy and splenic autotransplantation.
Next Document:  Hyperbilirubinemia following distal splenorenal shunt.