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Reliability of Airway Occlusion Pressure as an Index of Respiratory Motor Output.
MedLine Citation:
PMID:  23107621     Owner:  NLM     Status:  Publisher    
BACKGROUND: Airway occlusion pressure (P0.1) is used as an index of respiratory motor output; however, the reliability of P0.1 in this capacity has been not been sufficiently investigated. Therefore, the aim of our study was to examine the reliability of P0.1. METHODS: Eleven healthy subjects (7 men and 4 women) participated in our study. Subjects were placed in a supine position, and P0.1 was measured every 30 seconds for 5 minutes following a 1-minute period during which ventilation and respiratory frequency were measured. A total of 10 P0.1 values were obtained, and the intraclass correlation coefficient (ICC) was used to analyze reliability. ICC values from ICC (1, 2) to ICC (1, 10) were calculated following a number of measurements (k), where ICC (1, k) was increased sequentially from 2 to 10. RESULTS: ICC (1, 2) - ICC (1, 10) values were found to be between 0.877-0.960 (95% confidence intervals (CI): 0.565-0.966 and 0.912-0.987, respectively). When the target coefficient was set at 0.9, the ICC (1, 1) from 10 measurements was calculated a minimum of 4 times. CONCLUSIONS: Although a single measurement of P0.1 was somewhat reliable, the CIs indicated that it is necessary to determine the average value of 3 or more measurements. The minimum of 4 repeat measurements were required to obtain valid results, indicating that the current method of determining P0.1 by averaging the values from at least 4 repeated measurements is valid.
Takeshi Kera; Akiko Aihara; Takashi Inomata
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-26
Journal Detail:
Title:  Respiratory care     Volume:  -     ISSN:  0020-1324     ISO Abbreviation:  Respir Care     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7510357     Medline TA:  Respir Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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