Relevance of three-dimensional reconstructions of stain distributions for structural analysis of biomolecules. | |
MedLine Citation:
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PMID: 51815 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The relevance of a three-dimensional model of a protein molecule is discussed in the context of artefacts which inevitably occur during the preparation and imaging process. It is emphasized that even under optimistic assumptions, there-construction of a structure complementary to a given spatial stain distribution cannot, at resolutions below 10-15 A, be regarded as being identical with the real protein structure. |
Authors:
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W Baumeister; M Hahn |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hoppe-Seyler's Zeitschrift für physiologische Chemie Volume: 356 ISSN: 0018-4888 ISO Abbreviation: Hoppe-Seyler's Z. Physiol. Chem. Publication Date: 1975 Aug |
Date Detail:
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Created Date: 1975-12-28 Completed Date: 1975-12-28 Revised Date: 2000-12-18 |
Medline Journal Info:
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Nlm Unique ID: 2985060R Medline TA: Hoppe Seylers Z Physiol Chem Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 1313-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
MeSH Terms | |
Descriptor/Qualifier:
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Glutaral Mathematics Microscopy, Electron / methods Models, Molecular* Models, Structural* Protein Binding Protein Conformation* Staining and Labeling X-Ray Diffraction / methods |
Chemical | |
Reg. No./Substance:
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111-30-8/Glutaral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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