Document Detail


Relevance of homocysteine on brachial flow-mediated vasodilatation and carotid and femoral intima-media thickness in patients with hypercholesterolemia.
MedLine Citation:
PMID:  15165928     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The relevance of homocysteine to brachial flow-mediated vasodilatation and carotid and femoral intima-media thickness was investigated in 192 patients with hypercholesterolemia. Low-density lipoprotein cholesterol and homocysteine levels predicted brachial flow-mediated vasodilatation, internal carotid mean intima-media thickness, and intima-media thickening at all femoral sites. Homocysteine levels seem to be an additional factor in the initial atherosclerotic damage of patients with hypercholesterolemia.
Authors:
Gaetano Vaudo; Simona Marchesi; Donatella Siepi; Francesco Bagaglia; Rita Paltriccia; Matteo Pirro; Giuseppe Schillaci; Graziana Lupattelli; Elmo Mannarino
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  93     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-05-28     Completed Date:  2004-06-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1413-6, A9     Citation Subset:  AIM; IM    
Affiliation:
Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia School of Medicine, via Brunamonti 51, 06122 Perugia, Italy. gvaudo@unipg.it
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MeSH Terms
Descriptor/Qualifier:
Brachial Artery / physiology,  ultrasonography*
Carotid Artery, Internal / pathology,  ultrasonography*
Case-Control Studies
Cholesterol, LDL / blood
Female
Femoral Artery / pathology,  ultrasonography*
Homocysteine / blood*
Humans
Hypercholesterolemia / pathology,  physiopathology*
Male
Middle Aged
Regional Blood Flow / physiology
Regression Analysis
Risk Factors
Tunica Intima / pathology*
Tunica Media / pathology*
Vasodilation / physiology*
Chemical
Reg. No./Substance:
0/Cholesterol, LDL; 454-28-4/Homocysteine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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