| Release of oxytocin and substance P-like peptides from the rat posterior pituitary lobe incubated in situ after infusion of hypertonic solution into the third cerebral ventricle. | |
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MedLine Citation:
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PMID: 566506 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Release of oxytocin and Substance P-like peptides from the rat posterior pituitary lobe incubated in situ after infusion of hypertonic solution into the third cerebral ventricle. Acta Physiol. Pol., 1978, 29 (1): 9-16. The experiments were carried out on male rats. Under general urethane and chloralose anaesthesia the ventral surface of the hypothalamus and the pituitary gland were exposed by a transpharyngeal approach and the anterior pituitary lobe was entirely removed. The posterior lobe with the remaining neural and partially vascular connections with the hypothalamus was incubated in situ. Oxytocin and Substance P-like peptides were assayed biologically in six 20-min samples of the fluid outflow from the posterior pituitary lobe incubated in situ. At the beginning of collection of the fourth sample a hypertonic solution was infused into the third ventricle through a micropipette. This infusion increased significantly the release of oxytocin and insignificantly that of Substance P-like pepides from the posterior pituitary lobe into the incubation fluid. |
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Authors:
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M Orłowska-Majdak; B Werulik; W Z Traczyk |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta physiologica Polonica Volume: 29 ISSN: 0044-6033 ISO Abbreviation: Acta Physiol Pol Publication Date: 1978 Jan-Feb |
Date Detail:
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Created Date: 1978-08-14 Completed Date: 1978-08-14 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 2985166R Medline TA: Acta Physiol Pol Country: POLAND |
Other Details:
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Languages: eng Pagination: 9-16 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Female Hypertonic Solutions Injections, Intraventricular Jejunum / drug effects Lactation Mammary Glands, Animal / drug effects Oxytocin / pharmacology, secretion* Pituitary Gland, Posterior / secretion* Pregnancy Rats Substance P / pharmacology, secretion* |
| Chemical | |
Reg. No./Substance:
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0/Hypertonic Solutions; 33507-63-0/Substance P; 50-56-6/Oxytocin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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