Document Detail


Release of iron from ferritin by 6-hydroxydopamine under aerobic and anaerobic conditions.
MedLine Citation:
PMID:  2127409     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
6-hydroxydopamine (6-OHDA) proved to be a very effective agent for iron release from ferritin. Iron release was enhanced in the presence of SOD, catalase and under anaerobic conditions. Ascorbic acid, a well known agent able to release iron from ferritin, increased the amount of released iron in more than an additive manner when used in combination with 6-OHDA. Similar to 6-OHDA, 6-hydroxydopa (Topa) and 1,2,4-benzenetriol were also able to release iron in large amounts; in contrast, catecholamines and other benzenediols were comparatively ineffective.
Authors:
H N Lode; G Bruchelt; A G Rieth; D Niethammer
Related Documents :
1846749 - Internal intensity standards for heme protein uv resonance raman studies: excitation pr...
229899 - Denaturation of thermophilic ferricytochrome c-552 by acid, guanidine hydrochloride, an...
1316949 - Spectroscopic properties of the nitric oxide derivative of ferrous man, horse, and rumi...
21869929 - Dietary conjugated linoleic acid and hepatic steatosis: species-specific effects on liv...
6540979 - The relative effect of ascorbic acid on iron absorption from soy-based and milk-based i...
7893739 - Evidence for the importance of iron in the alpha-oxidation of 3-methyl-substituted fatt...
25174889 - Uncoupled hydrogen and volatile fatty acids generation in a two-step biotechnological a...
4269049 - The composition of cartilage proteoglycans. an investigation using high- and low-inonic...
15674019 - Development of a fluorescent high throughput assay for tau aggregation.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Free radical research communications     Volume:  11     ISSN:  8755-0199     ISO Abbreviation:  Free Radic. Res. Commun.     Publication Date:  1990  
Date Detail:
Created Date:  1991-04-15     Completed Date:  1991-04-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8709453     Medline TA:  Free Radic Res Commun     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  153-8     Citation Subset:  IM    
Affiliation:
Children's Hospital, Dept. Hematology and Oncology, University of Tuebingen, FRG.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aerobiosis
Anaerobiosis
Ascorbic Acid / pharmacology
Catalase / pharmacology
Ferritins / metabolism*
Hydroxydopamines / pharmacology*
Iron / metabolism*
Oxidopamine
Superoxide Dismutase / pharmacology
Chemical
Reg. No./Substance:
0/Hydroxydopamines; 1199-18-4/Oxidopamine; 50-81-7/Ascorbic Acid; 7439-89-6/Iron; 9007-73-2/Ferritins; EC 1.11.1.6/Catalase; EC 1.15.1.1/Superoxide Dismutase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Mutagenic activity of antineoplastic agents under conditions of normal and artificial modification
Next Document:  Enzymic pathways involved in cell response to H2O2.