Document Detail


Release by electrical stimulation of endogenous glutamate, gamma-aminobutyric acid, and other amino acids from slices of the rat medulla oblongata.
MedLine Citation:
PMID:  2562808     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Evidence was obtained for the release of amino acids by electrical stimulation of slices of regions of the rat medulla oblongata: rostral ventrolateral, caudal ventrolateral and caudal dorsomedial. There was a Ca2+-dependent, tetrodotoxin-sensitive increase in the efflux of aspartate, glutamate, gamma-aminobutyric acid (GABA), glycine, and beta-alanine in all regions examined. There were distinct regional differences in the relative amounts of amino acids released. These results provide evidence for the possible neurotransmitter role of aspartate, glutamate, GABA, glycine, and beta-alanine in these regions of the rat medulla oblongata.
Authors:
M Kihara; Y Misu; T Kubo
Related Documents :
12380848 - The role of amino-acid transmitters in the pathogenesis of delirium tremens: a brief re...
12573708 - Polyunsaturated fatty acids induce tight junctions to form in brain capillary endotheli...
1128168 - Positional analysis of isovaleroyl triglycerides using proton magnetic resonance with e...
19680818 - The utilization of gum tragacanth to improve the growth of rhodotorula aurantiaca and t...
1653998 - Proton-pump inhibition for acid-related disease.
3150128 - The influence of prolonged physical stress on gastric juice components in healthy man.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurochemistry     Volume:  52     ISSN:  0022-3042     ISO Abbreviation:  J. Neurochem.     Publication Date:  1989 Jan 
Date Detail:
Created Date:  1989-01-25     Completed Date:  1989-01-25     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  2985190R     Medline TA:  J Neurochem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  261-7     Citation Subset:  IM    
Affiliation:
Department of Pharmacology, Yokohama City University School of Medicine, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Amino Acids / metabolism*
Animals
Calcium / metabolism
Chromatography, High Pressure Liquid
Electric Stimulation
Glutamates / metabolism*
Glutamic Acid
Male
Medulla Oblongata / metabolism*
Rats
Rats, Inbred Strains
Tetrodotoxin / pharmacology
gamma-Aminobutyric Acid / metabolism*
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Glutamates; 4368-28-9/Tetrodotoxin; 56-12-2/gamma-Aminobutyric Acid; 56-86-0/Glutamic Acid; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Insulin binding to human astrocytoma cells and its effect on uridine incorporation into nucleic acid...
Next Document:  In vitro phosphorylation of bovine adrenal chromaffin cell tyrosine hydroxylase by endogenous protei...