Document Detail


Release of RNA--DNA-protein complex during differentiation of the water mould Allomyces arbuscula.
MedLine Citation:
PMID:  1033039     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A correlation between release of a nucleic acid protein complex into the external medium and sporangial differentiation was found. Conditions preventing differentiation also stopped the release. Lethal lysis is not involved in this release process. Extracellular nucleic acids are very heterogenous, consisting of nucleotides as well as acid-precipitable nucleic acids. RNA was found to be associated with proteins and a hetero-duplex RNA--DNA associated with this nucleoprotein. Some speculations are presented about possible correlation between the release of nucleoprotein complexes and the intracellular events of differentiation.
Authors:
E W Khandjian; G Turian
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell differentiation     Volume:  5     ISSN:  0045-6039     ISO Abbreviation:  Cell Differ.     Publication Date:  1976 Oct 
Date Detail:
Created Date:  1977-01-28     Completed Date:  1977-01-28     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  0342640     Medline TA:  Cell Differ     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  171-88     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cell Differentiation / drug effects
Centrifugation, Density Gradient
Chromatography
Chytridiomycota / cytology*,  metabolism
Cycloheximide / pharmacology
DNA / analysis
Dactinomycin / pharmacology
Deoxyribonucleases
Deoxyribonucleoproteins / analysis,  metabolism*
Fungal Proteins / metabolism*
Fungi / cytology*
Nucleoproteins / analysis,  metabolism*
Proflavine / pharmacology
RNA / analysis
Ribonucleases
Ribonucleoproteins / analysis,  metabolism
Chemical
Reg. No./Substance:
0/Deoxyribonucleoproteins; 0/Fungal Proteins; 0/Nucleoproteins; 0/Ribonucleoproteins; 50-76-0/Dactinomycin; 63231-63-0/RNA; 66-81-9/Cycloheximide; 9007-49-2/DNA; 92-62-6/Proflavine; EC 3.1.-/Deoxyribonucleases; EC 3.1.-/Ribonucleases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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