Document Detail


Relaxin augments the inflammatory IL6 response in the choriodecidua.
MedLine Citation:
PMID:  22386961     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
SUMMARY: RLN augments the inflammatory responses induced by IL1B or LPS in chorionic cytotrophoblasts and decidual fibroblasts.
Authors:
J S Horton; S Y Yamamoto; G D Bryant-Greenwood
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2012-03-03
Journal Detail:
Title:  Placenta     Volume:  33     ISSN:  1532-3102     ISO Abbreviation:  Placenta     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-02     Completed Date:  2012-08-03     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  8006349     Medline TA:  Placenta     Country:  England    
Other Details:
Languages:  eng     Pagination:  399-407     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Cell and Molecular Biology, University of Hawaii, John A. Burns School of Medicine, 651 Ilalo Street, Bioscience Building, Honolulu, HI 96813, USA. jshorton@hawaii.edu
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MeSH Terms
Descriptor/Qualifier:
Cyclic AMP / metabolism
Extraembryonic Membranes / metabolism*
Female
Humans
Interleukin-1beta / metabolism
Interleukin-6 / metabolism*,  secretion
Receptors, G-Protein-Coupled / metabolism
Receptors, Peptide / metabolism
Relaxin / metabolism*
Toll-Like Receptor 4 / metabolism
Trophoblasts / metabolism*,  secretion
Grant Support
ID/Acronym/Agency:
HD24314/HD/NICHD NIH HHS; R01 HD024314-10/HD/NICHD NIH HHS; U54 RR014607-10/RR/NCRR NIH HHS; U54 RR014607-10/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/IL1B protein, human; 0/IL6 protein, human; 0/Interleukin-1beta; 0/Interleukin-6; 0/RXFP1 protein, human; 0/Receptors, G-Protein-Coupled; 0/Receptors, Peptide; 0/TLR4 protein, human; 0/Toll-Like Receptor 4; 60-92-4/Cyclic AMP; 9002-69-1/Relaxin
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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