Document Detail

Relative significance of isolated infantile convulsions as a primary cause of focal epilepsy.
MedLine Citation:
PMID:  113207     Owner:  NLM     Status:  MEDLINE    
Isolated infantile convulsions were noted in 206 patients (13%) of 1,572 patients who underwent cortical resection for medically refractory focal epilepsy at the Montreal Neurological Institute over the period 1928 through 1977. In 59 patients (29% of the 206), the isolated infantile convulsion was associated with an identifiable febrile systemic or neural illness. In 54 patients (26%), there was a definite history of cerebral birth injury in addition to the isolated infantile convulsions. Twenty patients (10%) had some other potential etiological factor for the later development of seizures, such as postnatal head injury, Sturge-Weber syndrome, etc., in addition to the isolated infantile convulsions. In 95 patients, 6% of the total 1,572 patient series and 41% of those with isolated infantile convulsions, the latter was the sole apparent cause for the later development of recurring seizures. Although this was the case in a small but significant percentage in this series of patients, more frequently, the isolated infantile convulsion represents a manifestation of invasion of the brain by an infectious agent of a systemic or brain disease, or is a harbinger of the later development of a seizure tendency due to some other preexisting etiological factor.
T Rasmussen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Epilepsia     Volume:  20     ISSN:  0013-9580     ISO Abbreviation:  Epilepsia     Publication Date:  1979 Aug 
Date Detail:
Created Date:  1979-11-29     Completed Date:  1979-11-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2983306R     Medline TA:  Epilepsia     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  395-401     Citation Subset:  IM    
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MeSH Terms
Birth Injuries / complications
Brain Injuries / complications
Brain Neoplasms / complications
Epilepsies, Partial / complications,  etiology,  surgery*
Epilepsy, Temporal Lobe / etiology,  surgery
Seizures, Febrile / complications
Spasms, Infantile / complications*

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