| Relative cerebral blood volume measurements in intracranial mass lesions: interobserver and intraobserver reproducibility study. | |
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MedLine Citation:
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PMID: 12202717 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To assess inter- and intraobserver reproducibility for different techniques of measuring relative cerebral blood volume (rCBV) in patients with intracranial mass lesions. MATERIALS AND METHODS: Three independent observers (neuroradiology fellows) who were blinded to the histopathologic diagnosis performed rCBV measurements in 50 patients with various intracranial mass lesions. Three different methods were compared. With method 1, placement of a single region of interest was guided by a color overlay map. With methods 2 and 3, the highest rCBV value and the mean of repeated rCBV measurements, respectively, were recorded. Calculations of the intraclass correlation coefficient, coefficient of variation (CV), and descriptive statistics were used to determine the levels of reproducibility. A multiple linear regression model was used to evaluate for possible explanatory factors for interobserver variance. RESULTS: Method 2 had, overall, the best reproducibility of all techniques, with an intraclass interobserver correlation coefficient of 0.71 (indicating good agreement), interobserver CV of 30%, and intraobserver CV in the range of 32%-41%. Measurement variations between observers correlated significantly (P <.001) with increasing rCBV values. CONCLUSION: In this study, interobserver and intraobserver reproducibility of rCBV measurements were clinically acceptable. |
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Authors:
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Stephan G Wetzel; Soonmee Cha; Glyn Johnson; Peter Lee; Meng Law; David L Kasow; Sean D Pierce; Xiaonan Xue |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Radiology Volume: 224 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 2002 Sep |
Date Detail:
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Created Date: 2002-08-30 Completed Date: 2002-10-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 797-803 Citation Subset: AIM; IM |
Copyright Information:
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Copyright RSNA, 2002 |
Affiliation:
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Department of Radiology, New York University School of Medicine, 550 First Ave, NY 10016, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Blood Volume Determination / methods* Brain Neoplasms / physiopathology* Cerebrovascular Circulation / physiology* Child Child, Preschool Female Humans Magnetic Resonance Imaging* Male Middle Aged Observer Variation Reproducibility of Results |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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