| Relationships between telocytes and cardiomyocytes during pre- and post-natal life. | |
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MedLine Citation:
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PMID: 20455994 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Evidence has been given that the adult heart contains a specific population of stromal cells lying in close spatial relationship with cardiomyocytes and with cardiac stem cells in sub-epicardial cardiogenic niches. Recently termed 'telocytes' because of their long cytoplasmic processes embracing the parenchymal cells, these cells have been postulated to be involved in heart morphogenesis. In our opinion, investigating the occurrence and morphology of telocytes during heart histogenesis may shed further light on this issue. Our findings show that typical telocytes are present in the mouse heart by early embryonic to adult life. These cells closely embrace the growing cardiomyocytes with their long, slender cytoplasmic processes. Hence, in the developing myocardium, telocytes may play nursing and guiding roles for myocardial precursors to form the correct three-dimensional tissue architectural pattern, as previously suggested. |
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Authors:
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Maria-Simonetta Faussone-Pellegrini; D Bani |
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Publication Detail:
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Type: Journal Article Date: 2010-04-23 |
Journal Detail:
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Title: Journal of cellular and molecular medicine Volume: 14 ISSN: 1582-4934 ISO Abbreviation: J. Cell. Mol. Med. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-07-21 Completed Date: 2010-10-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101083777 Medline TA: J Cell Mol Med Country: England |
Other Details:
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Languages: eng Pagination: 1061-3 Citation Subset: IM |
Affiliation:
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Department of Anatomy, Histology and Forensic Medicine, University of Florence, Florence, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn Embryo, Mammalian / cytology, metabolism Immunohistochemistry Mice Myocardium / cytology*, ultrastructure Myocytes, Cardiac / cytology*, metabolism, ultrastructure |
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