Document Detail


Relationships between serial childhood adiposity measures and adult blood pressure: The Fels longitudinal study.
MedLine Citation:
PMID:  20865760     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: Several studies have shown that causes of adult hypertension arise in childhood, and obesity may be a potential cause or at least a mitigating factor in this development. Body mass index is a well studied obesity metric, yet other potential adiposity measures such as percent body fat and waist circumference have been somewhat less considered. The purpose of this study is to determine associations between these alternative serial childhood adiposity measures and adulthood blood pressure.
METHODS: Measurements from participants in the Fels Longitudinal Study were used to summarize childhood adiposity, represented by childhood measurements of percent body fat and height-adjusted waist circumference. These subjects also provided systolic and diastolic blood pressure as adults. Childhood adiposity levels were categorized as high or low as compared to the respective upper quartile, and associations with adult blood pressure were measured using Poisson regression to estimate the number of expected occurrences of elevated adiposity during childhood. Adult lifestyle covariates and adiposity were accounted for using multiple linear regression.
RESULTS: Summary indices of the childhood adiposity measures were significantly associated with both adult blood pressure metrics in men and women, though some of these associations were altered or reduced in the presence of adult lifestyle characteristics and adult adiposity measures.
CONCLUSIONS: Childhood measures of percent body fat and height-adjusted waist circumference have an effect on adult blood pressure, though the effect can be mitigated by adult lifestyles.
Authors:
Roy Travis Sabo; Zheng Lu; Stephen Daniels; Shumei S Sun
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  American journal of human biology : the official journal of the Human Biology Council     Volume:  22     ISSN:  1520-6300     ISO Abbreviation:  Am. J. Hum. Biol.     Publication Date:    2010 Nov-Dec
Date Detail:
Created Date:  2010-10-19     Completed Date:  2011-02-03     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  8915029     Medline TA:  Am J Hum Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  830-5     Citation Subset:  IM    
Copyright Information:
© 2010 Wiley-Liss, Inc.
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MeSH Terms
Descriptor/Qualifier:
Adiposity / physiology*
Adolescent
Adult
Blood Pressure / physiology*
Child
Female
Health Behavior
Health Surveys
Humans
Life Style
Longitudinal Studies
Male
Grant Support
ID/Acronym/Agency:
DK 071485/DK/NIDDK NIH HHS; HD 12252/HD/NICHD NIH HHS; HL 072838/HL/NHLBI NIH HHS; R01 DK071485/DK/NIDDK NIH HHS; R01 HD012252/HD/NICHD NIH HHS; R01 HD060913/HD/NICHD NIH HHS; R01 HL072838/HL/NHLBI NIH HHS; R01 HL072838-01A1/HL/NHLBI NIH HHS; R01 HL072838-05/HL/NHLBI NIH HHS; R01HD038356/HD/NICHD NIH HHS; R01HD060913/HD/NICHD NIH HHS; R01HL072838-05/HL/NHLBI NIH HHS; U01 HL101064/HL/NHLBI NIH HHS; U01 HL101064-01/HL/NHLBI NIH HHS; U01HL101064/HL/NHLBI NIH HHS
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