Document Detail

Relationships between pulse wave velocity and heart rate variability in healthy men with a range of moderate-to-vigorous physical activity levels.
MedLine Citation:
PMID:  17013591     Owner:  NLM     Status:  MEDLINE    
Pulse wave velocity (PWV) is associated with heart rate variability (HRV) in 24-39-year-old men. This study of 40-65-year-old men ranging in moderate-to-vigorous physical activity levels investigated whether (a) PWV is related to spectral HRV, (b) using normalised units for HRV influences that relationship, and (c) HRV predicts PWV when other factors, including age and blood pressure, are accounted for. Subjects were healthy men (N=115), mean (SD) age 50.8 (7.1) years. Carotid-femoral PWV was measured using Complior. HRV was derived from a 5 min ECG for total, high-frequency, and low-frequency power (TP, HF, and LF, respectively), the LF/HF ratio, and normalised units for HF (HFnu) and LF (LFnu). Non-parametric data were natural log-transformed. PWV was 8.5 (1.4) m s-1. TP, HF, LF, LF/HF, HFnu and LFnu were 1908 (2195) m s2, 577 (1034) m s2, 457 (514) m s2, 1.5 (1.3), 46.8 (17.9), and 49.4 (19.4), respectively. PWV was inversely associated with TP (R2=0.061, p=0.008), HF (R2=0.095, p=0.001), LF (R2=0.086, p=0.002) and HFnu (R2=0.040, p=0.031), but was not associated with LF/HF (R2=0.020, p=0.136) or LFnu (R2=0.028 p=0.076). Only age and systolic blood pressure (adjusted R2=0.306, p<0.001) predicted PWV in multivariate analysis. This study has shown that PWV was weakly associated with TP and HF. The use of normalised units only influenced the relationship between PWV and LF. Finally, relationships between PWV and HRV are mediated through age and systolic blood pressure in this population of men ranging in moderate-to-vigorous physical activity level.
G M Perkins; A Owen; I L Swaine; J D Wiles
Publication Detail:
Type:  Journal Article     Date:  2006-09-30
Journal Detail:
Title:  European journal of applied physiology     Volume:  98     ISSN:  1439-6319     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-12-07     Completed Date:  2007-01-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  516-23     Citation Subset:  IM    
Sport Science, Tourism and Leisure, Canterbury Christ Church University, and Kent and Canterbury Hospital, Kent, CT1 1QU, UK.
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MeSH Terms
Anaerobic Threshold / physiology
Blood Flow Velocity / physiology*
Blood Pressure / physiology
Carotid Arteries / physiology
Femoral Artery / physiology
Heart Rate / physiology*
Middle Aged
Multivariate Analysis
Oxygen Consumption / physiology
Physical Fitness / physiology*
Regional Blood Flow / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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