Document Detail

Relationships between psychological measurements and cerebral organic changes in Alzheimer's disease.
MedLine Citation:
PMID:  7388699     Owner:  NLM     Status:  MEDLINE    
Twenty-two patients were carefully defined as having progressive dementia without other known cause and not complicated by clinical or laboratory evidence of multiinfarct dementia. Their degree of dementia measured by the ESD correlated highly with EEG disturbance (r=-0.79). The LPRS correlated 0.73 with ventricular enlargement. Although the EEG and CT scan only correlated significantly with each other in advanced cases, a combined index of EEG and CT Scan change, (Physical Measures Index) achieved a correlation of 0.93 with a combined index of psychological change (Psychological Measures Index). The results indicate the possiblity of using physical and psychological measures to monitor quantitative change in Alzheimer's Disease, the EEG contributing more initially and the CT scan more in the most advanced cases.
H Merskey; M J Ball; W T Blume; A J Fox; H Fox; E L Hersch; V A Kral; R B Palmer
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques     Volume:  7     ISSN:  0317-1671     ISO Abbreviation:  Can J Neurol Sci     Publication Date:  1980 Feb 
Date Detail:
Created Date:  1980-09-28     Completed Date:  1980-09-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0415227     Medline TA:  Can J Neurol Sci     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  45-9     Citation Subset:  IM    
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MeSH Terms
Alzheimer Disease / diagnosis*,  pathology,  physiopathology
Dementia / diagnosis*
Psychiatric Status Rating Scales
Psychological Tests
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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