Document Detail


Relationships between organohalogen contaminants and blood plasma clinical-chemical parameters in chicks of three raptor species from Northern Norway.
MedLine Citation:
PMID:  19800686     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Organohalogen contaminants (OHCs) may affect various physiological parameters in birds including blood chemistry. We therefore examined blood plasma clinical-chemical parameters and OHCs in golden eagle, white-tailed eagle and goshawk chicks from Northern Norway. Correlation analyses on pooled data showed that alkaline phosphatase (ALKP), glucose and creatinine were significantly negatively correlated to various OHCs (all: p<0.05; r: -0.43 to -0.55; n=23), while alanine aminotransferase (ALAT), total protein, cholesterol, uric acid, total bilirubin, ratios protein:creatinine and uric acid:creatinine were significantly positively correlated to various OHCs (all: p<0.05; r: 0.43-0.96). Based on these relationships, we suggest that the OHC concentrations found in certain raptor chicks of Northern Scandinavia may impact blood plasma biochemistry in a way that indicates impacts on liver, kidney, bone, endocrinology and metabolism. In order to elaborate further on these relationships and mechanisms, we recommend that a larger study should take place in the near future.
Authors:
Christian Sonne; Jan Ove Bustnes; Dorte Herzke; Veerle L B Jaspers; Adrian Covaci; Duncan J Halley; Truls Moum; Igor Eulaers; Marcel Eens; Rolf A Ims; Sveinn A Hanssen; Kjell Einar Erikstad; Trond Johnsen; Lisbeth Schnug; Frank F Rig??t; Asger L Jensen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-10-03
Journal Detail:
Title:  Ecotoxicology and environmental safety     Volume:  73     ISSN:  1090-2414     ISO Abbreviation:  Ecotoxicol. Environ. Saf.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-11-10     Completed Date:  2010-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7805381     Medline TA:  Ecotoxicol Environ Saf     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7-17     Citation Subset:  IM    
Affiliation:
Arhus University, National Environmental Research Institute, Department of Arctic Environment, Frederiksborgvej 399, PO Box 358, DK-4000 Roskilde, Denmark. csh@dmu.dk
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MeSH Terms
Descriptor/Qualifier:
Alkaline Phosphatase / blood
Animals
Bilirubin / blood
Blood Chemical Analysis*
Blood Glucose / analysis
Blood Proteins / analysis
Cholesterol / blood
Creatinine / blood
Eagles
Environmental Pollutants / toxicity*
Flame Retardants
Fluorocarbons / toxicity
Hawks
Hydrocarbons, Brominated / toxicity
Hydrocarbons, Chlorinated / toxicity*
Norway
Polychlorinated Biphenyls / toxicity*
Principal Component Analysis
Uric Acid / blood
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Blood Proteins; 0/Environmental Pollutants; 0/Flame Retardants; 0/Fluorocarbons; 0/Hydrocarbons, Brominated; 0/Hydrocarbons, Chlorinated; 0/Polychlorinated Biphenyls; 57-88-5/Cholesterol; 60-27-5/Creatinine; 635-65-4/Bilirubin; 69-93-2/Uric Acid; EC 3.1.3.1/Alkaline Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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