Document Detail

Relationships between haemodynamic parameters and concentrations of atrial natriuretic peptide in human plasma.
MedLine Citation:
PMID:  2956385     Owner:  NLM     Status:  MEDLINE    
Plasma concentrations of the atrial natriuretic peptide (ANP) were measured during cardiac catheterization in 289 patients with heart disease. It was elevated in all types of cardiac disease investigated, irrespective of the nature and duration of the disease. Close relationships were observed between the elevated ANP concentrations and the increased right and/or left atrial pressure. Further increments in ANP concentration were measured during exercise in direct response to the rise in mean pulmonary artery pressure. Thus, ANP concentrations may be regarded as a non-invasive marker of the haemodynamic burden in cardiac disease.
R Dietz; R E Lang; J Purgaj; A Merkel; A Schömig; W Kübler
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of hypertension. Supplement : official journal of the International Society of Hypertension     Volume:  4     ISSN:  0952-1178     ISO Abbreviation:  J Hypertens Suppl     Publication Date:  1986 Dec 
Date Detail:
Created Date:  1987-09-16     Completed Date:  1987-09-16     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8501422     Medline TA:  J Hypertens Suppl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  S512-5     Citation Subset:  IM    
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MeSH Terms
Atrial Natriuretic Factor / blood*
Cardiomyopathies / physiopathology
Cardiomyopathy, Dilated / physiopathology
Chronic Disease
Heart Diseases / blood
Heart Valve Diseases / physiopathology
Osmolar Concentration
Physical Exertion
Reg. No./Substance:
85637-73-6/Atrial Natriuretic Factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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