Document Detail


Relationships between dynamic contrast-enhanced MRI findings and pattern of invasion for tongue carcinoma.
MedLine Citation:
PMID:  16596208     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to evaluate the effectiveness of dynamic contrast-enhanced MRI (DC-MRI) for assessing the pattern of invasion of tongue carcinomas. We studied 20 cases of squamous cell carcinoma of the tongue that showed peripheral enhancement patterns on DC-MRI. The diameter of each tumor was >2.0 cm and no apparent artifacts were seen. The signal enhancement to noise ratio (SE/N) of the regions of interest, which were located in the central and peripheral regions of the tumor, were measured using DC-MRI, while maximum SE/N, %-wash out, and the ascending rate of SE/N were also calculated. The histopathological pattern of invasion was assessed in each case and used to classify them into clear (13 cases) and diffuse (7 cases) groups, after which the 4 parameters were compared between the 2 groups. The ascending rate of SE/N in the peripheral region was significantly lower in the diffuse group (p=0.047). There were no other significant differences between the 2 groups for any parameter in either tumor region. These results suggest that DC-MRI is able to show the histopathological pattern of invasion into surrounding structures.
Authors:
Yasunori Ariyoshi; Masashi Shimahara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Oncology reports     Volume:  15     ISSN:  1021-335X     ISO Abbreviation:  Oncol. Rep.     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-04-05     Completed Date:  2006-06-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9422756     Medline TA:  Oncol Rep     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  1339-43     Citation Subset:  IM    
Affiliation:
Department of Oral Surgery, Osaka Medical College, Takatsuki City, Osaka 569-8686, Japan. ora009@poh.osaka-med.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Carcinoma, Squamous Cell / diagnosis
Contrast Media*
Female
Gadolinium DTPA / diagnostic use*
Humans
Image Enhancement*
Imaging, Three-Dimensional*
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Neoplasm Invasiveness / diagnosis*
Tongue Neoplasms / diagnosis*
Chemical
Reg. No./Substance:
0/Contrast Media; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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