Document Detail

Relationships between coronary calcification detected at electron beam computed tomography and percutaneous transluminal coronary angioplasty results in coronary artery disease patients.
MedLine Citation:
PMID:  12541111     Owner:  NLM     Status:  MEDLINE    
Our objective was to assess the relationship between coronary artery calcification and outcomes of percutaneous transluminal coronary angioplasty (PTCA). Electron beam computed tomography (EBCT) was performed in 80 patients with coronary artery disease (CAD) who underwent PTCA. The calcium score in each coronary artery vessel was estimated (in Agatston units) and compared with the occurrence of complications and restenosis. Angioplasty had been performed in 96 coronary artery segments with stenosis in 80 patients. The average calcium score in the unsuccessful PTCA segments was significantly higher than in ones with successful results. For complications these values were 65.0+/-79.9 and 27.0+/-44.7, respectively ( p=0.02), and for restenosis 63.9+/-87.9 and 27.3+/-41.3, respectively ( p=0.03). Applying receiver operating characteristics analysis we determined sensitivity and specificity of EBCT for forecasting complications and restenosis. The best cut-off value of calcium score in segment of PTCA for prediction of restenosis was 27 (sensitivity 73%, specificity 67%), and for prediction of complications 29 (sensitivity 80%, specificity 74%). Coronary segments with extensive calcification were not optimal target lesions for PTCA. Analysis of coronary calcium score should be taken into consideration during planning of endovascular coronary interventions.
V Sinitsyn; M Belkind; Y Matchin; A Lyakishev; V Naumov; S Ternovoy
Publication Detail:
Type:  Journal Article     Date:  2002-06-28
Journal Detail:
Title:  European radiology     Volume:  13     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2003-01-23     Completed Date:  2003-05-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  62-7     Citation Subset:  IM    
Institute of Cardiology, Cardiology Research Center, 3d Cherepkovskaya Street, 15-A, 121552 Moscow, Russia.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary* / adverse effects
Calcinosis / radiography*
Coronary Angiography*
Coronary Disease / radiography*,  therapy
Coronary Restenosis
Coronary Stenosis / radiography*
Middle Aged
ROC Curve
Sensitivity and Specificity
Tomography, X-Ray Computed*

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