Document Detail


Relationships between air swallowing, intragastric air, belching and gastro-oesophageal reflux.
MedLine Citation:
PMID:  15916621     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: With each swallow a certain amount of air is transported to the stomach. The stomach protects itself against excessive distention by swallowed air through belching (gas reflux). The mechanism of belching (transient lower oesophageal sphincter relaxation) is also one of the mechanisms underlying gastro-oesophageal reflux. AIM: To investigate whether swallowing of air leads to an increase in size of the intragastric air bubble and to gastro-oesophageal reflux. METHODS: Multichannel intraluminal impedance measurement was used to quantify the incidence of swallowing of air in 20 healthy volunteers before and after a meal. Radiography was used to measure the size of the intragastric air bubble. Gastro-oesophageal reflux was assessed by concurrent impedance and pH measurement. RESULTS: The rate of air swallowing was correlated to the size of the intragastric air bubble postprandially and to the rate of gaseous gastro-oesophageal reflux. The number of air swallows and the size of the intragastric air bubble did not correlate with the number of liquid acid and non-acid reflux episodes. CONCLUSIONS: In healthy subjects, air swallowing promotes belching but does not facilitate acid reflux.
Authors:
A J Bredenoord; B L A M Weusten; R Timmer; L M A Akkermans; A J P M Smout
Publication Detail:
Type:  Clinical Conference; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society     Volume:  17     ISSN:  1350-1925     ISO Abbreviation:  Neurogastroenterol. Motil.     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-05-26     Completed Date:  2005-06-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9432572     Medline TA:  Neurogastroenterol Motil     Country:  England    
Other Details:
Languages:  eng     Pagination:  341-7     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology, Sint Antonius Hospital, Nieuwegein, The Netherlands. a.bredenoord@antonius.net
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MeSH Terms
Descriptor/Qualifier:
Adult
Air
Deglutition / physiology*
Eating / physiology
Electric Impedance
Eructation / physiopathology*,  radiography
Esophagus / physiology
Female
Fluoroscopy
Gastroesophageal Reflux / physiopathology*,  radiography
Humans
Male
Manometry
Middle Aged
Postprandial Period
Stomach / anatomy & histology,  physiology*,  radiography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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