Document Detail

Relationships between IGF-I and weight Z score, BMI, tricipital skin-fold thickness, type of feeding in healthy infants in the first 5 months of life.
MedLine Citation:
PMID:  15802902     Owner:  NLM     Status:  MEDLINE    
AIM: To determine the concentration of insulin-like growth factor-I (IGF-I) in exclusively breast-fed (BF) and formula-fed (FF) infants in the first 5 months of life and to study the relationship between the IGF-I level and Z score for weight, body mass index (BMI) and tricipital skin-fold thickness. METHODS: We performed a cross-sectional study in order to evaluate serum IGF-I in 97 age-matched healthy term infants: 50 FF and 47 BF. RESULTS: FF infants showed higher values of IGF-I (38.9 +/- 12 ng/ml) when compared to BF infants (26.7 +/- 11.6 ng/ml; p < 0.05). A positive correlation was found between IGF-I values and Z score for weight (p < 0.001), BMI (p = 0.014), tricipital skin-fold thickness (p = 0.043) and age (p = 0.02). CONCLUSION: These results show that the IGF-I serum concentration is higher in FF infants. The observed association between IGF-I and Z score for weight, BMI, tricipital skin-fold thickness confirms the effect of different infant feeding on body size.
F Savino; G E Nanni; S Maccario; R Oggero; G C Mussa
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2005-03-29
Journal Detail:
Title:  Annals of nutrition & metabolism     Volume:  49     ISSN:  0250-6807     ISO Abbreviation:  Ann. Nutr. Metab.     Publication Date:    2005 Mar-Apr
Date Detail:
Created Date:  2005-05-27     Completed Date:  2005-10-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8105511     Medline TA:  Ann Nutr Metab     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  83-7     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2005 S. Karger AG, Basel.
Department of Paediatrics, University of Turin, Regina Margherita Hospital, Turin, Italy.
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MeSH Terms
Analysis of Variance
Arm / physiology
Body Mass Index*
Body Weight / physiology*
Breast Feeding / statistics & numerical data*
Cross-Sectional Studies
Infant Formula / administration & dosage,  statistics & numerical data*
Infant, Newborn
Insulin-Like Growth Factor I / metabolism*
Reference Values
Skinfold Thickness*
Reg. No./Substance:
67763-96-6/Insulin-Like Growth Factor I

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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