Document Detail


Relationship of urinary arsenic metabolites to intake estimates in residents of the Red River Delta, Vietnam.
MedLine Citation:
PMID:  19004533     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study investigated the status of arsenic (As) exposure from groundwater and rice, and its methylation capacity in residents from the Red River Delta, Vietnam. Arsenic levels in groundwater ranged from <1.8 to 486 microg/L. Remarkably, 86% of groundwater samples exceeded WHO drinking water guideline of 10 microg/L. Also, estimated inorganic As intake from groundwater and rice were over Provisional Tolerable Weekly Intake (15 microg/week/kg body wt.) by FAO/WHO for 92% of the residents examined. Inorganic As and its metabolite (monomethylarsonic acid and dimethylarsinic acid) concentrations in human urine were positively correlated with estimated inorganic As intake. These results suggest that residents in these areas are exposed to As through consumption of groundwater and rice, and potential health risk of As is of great concern for these people. Urinary concentration ratios of dimethylarsinic acid to monomethylarsonic acid in children were higher than those in adults, especially among men, indicating greater As methylation capacity in children.
Authors:
Tetsuro Agusa; Takashi Kunito; Tu Binh Minh; Pham Thi Kim Trang; Hisato Iwata; Pham Hung Viet; Shinsuke Tanabe
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-11-12
Journal Detail:
Title:  Environmental pollution (Barking, Essex : 1987)     Volume:  157     ISSN:  1873-6424     ISO Abbreviation:  Environ. Pollut.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2008-12-08     Completed Date:  2009-04-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804476     Medline TA:  Environ Pollut     Country:  England    
Other Details:
Languages:  eng     Pagination:  396-403     Citation Subset:  IM    
Affiliation:
Center for Marine Environmental Studies (CMES), Ehime University, Bunkyo-cho 2-5, Matsuyama 790-8577, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Factors
Arsenic / analysis,  urine*
Diet / statistics & numerical data
Environmental Monitoring / methods
Female
Food Contamination / analysis*
Humans
Male
Methylation
Oryza sativa / chemistry
Risk Assessment / methods
Rivers / chemistry
Sex Factors
Vietnam
Water Pollutants, Chemical / analysis,  urine*
Water Supply / analysis
Young Adult
Chemical
Reg. No./Substance:
0/Water Pollutants, Chemical; 7440-38-2/Arsenic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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