Document Detail

Relationship of total 25-OH vitamin D concentrations to Indices of Multiple Deprivation: geoanalysis of laboratory results.
MedLine Citation:
PMID:  23148282     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Vitamin D deficiency appears to be widespread and associated with ethnicity and economic status. Geography is the key to virtually all national statistics. It provides a structure for collecting, processing, storing and aggregating data. Linking geographic data to laboratory data allows analysis of the association of laboratory data with economic indicators.
METHODS: The laboratory information system was searched to create a data-set of total 25-OH vitamin D concentrations, which was then linked to economic (Indices of Multiple Deprivation [IMD]) and ethnicity data using postcodes geocoded to Lower Super Output Areas (LSOAs).
RESULTS: A total of 12422 25-OH vitamin D requests were received during the time period searched. A total of 12167 of these had associated postcodes that would allow georeferencing to LSOAs. The median total 25-OH vitamin D was 24.5 nmol/L (5.3-99.0; 2.5-97.5th percentile). Statistically significant (Spearman rank) correlations were found between median 25-OH vitamin D (nmol/L) and percentage of non-White population and percentage of non-White population and IMD. No statistically significant correlation between median 25-OH vitamin D concentration and IMD was found; however, a statistically significant correlation between percentage of population classified as severely deficient and IMD was found.
CONCLUSIONS: In summary, vitamin D deficiency is widespread and is related to ethnicity; it does not appear to be related to economic status except in cases of severe vitamin D deficiency.
Craig Webster
Publication Detail:
Type:  Journal Article     Date:  2012-11-12
Journal Detail:
Title:  Annals of clinical biochemistry     Volume:  50     ISSN:  1758-1001     ISO Abbreviation:  Ann. Clin. Biochem.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-02-18     Completed Date:  2013-07-30     Revised Date:  2013-12-04    
Medline Journal Info:
Nlm Unique ID:  0324055     Medline TA:  Ann Clin Biochem     Country:  England    
Other Details:
Languages:  eng     Pagination:  31-8     Citation Subset:  IM    
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MeSH Terms
African Continental Ancestry Group
Asian Continental Ancestry Group
Body Mass Index
European Continental Ancestry Group
Geography, Medical
Great Britain / epidemiology
Social Class
Vitamin D / blood*
Vitamin D Deficiency / blood*,  ethnology*
Reg. No./Substance:
1406-16-2/Vitamin D
Comment In:
Ann Clin Biochem. 2013 Nov;50(Pt 6):622-3   [PMID:  23880619 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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