Document Detail

Relationship of sonographic wall components of the brachial artery to hypertension and coronary atherosclerosis.
MedLine Citation:
PMID:  16235771     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to determine whether sonographically assessed intimal (echodense, ED) or medial (echolucent, EL) thickening of the brachial artery is associated with coronary artery disease (CAD) and/or arterial hypertension (HT). In 201 patients the ED and EL wall components, as well as the total wall thickness of the brachial artery, were measured with high-resolution ultrasound (13 MHz). According to the presence or absence of CAD and HT, the patients were divided into four groups: no HT and no CAD (n = 26, group 1), CAD (> or = 30% diameter stenosis in > or = 1 major branch) only (n = 63, group 2), HT only (n = 34, group 3), and HT and CAD (n = 78, group 4). EL (p < 0.001) and combined wall thickness (p < 0.001), but not the ED wall component, were significantly different between the groups, with the highest values occurring in group 4. On logistic regression analyses adjusting for age, coronary risk factors and body mass index, EL, but not ED, thickness correlated independently with the presence of CAD (p = 0.04) and HT (p < 0.001). High-resolution ultrasound examination of the brachial artery wall structure may contribute to the noninvasive assessment of early atherosclerosis.
Matthias Frick; Hannes F Alber; Alexander Rinner; Alois Suessenbacher; Hanno Ulmer; Severin P Schwarzacher; Otmar Pachinger; Franz Weidinger
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Vascular medicine (London, England)     Volume:  10     ISSN:  1358-863X     ISO Abbreviation:  Vasc Med     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-10-20     Completed Date:  2005-12-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9610930     Medline TA:  Vasc Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  185-90     Citation Subset:  IM    
Clinical Division of Cardiology, Innsbruck Medical University, Innsbruck, Austria.
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MeSH Terms
Brachial Artery / physiopathology,  ultrasonography*
Coronary Artery Disease / physiopathology,  ultrasonography*
Endothelium, Vascular / physiopathology
Hypertension / physiopathology,  ultrasonography*
Middle Aged
Regional Blood Flow / physiology
Risk Factors
Tunica Intima / ultrasonography*
Tunica Media / ultrasonography*
Vasodilation / physiology

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