| Relationship of mouse body weight and food consumption/wastage to cage shelf level. | |
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MedLine Citation:
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PMID: 6664066 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The relationships between the shelf level at which mice were housed and body weight and food consumption/wastage were examined by analyzing data obtained from the first 9 months of a carcinogenic dose-response study carried out in 24,192 female BALB/c mice using 2-acetylaminofluorene (2-AAF) as the carcinogen. Each cage, containing four mice, was maintained on a rack at a given shelf level throughout the course of the experiment to allow analysis of data by shelf level. The amount of food removed from each feeder and the body weight of each mouse was measured weekly. Average body weight gain during the first 12 weeks was lowest on the top shelf, highest on the next two shelves, and progressively lower as the shelf approached the lowest level on the rack. Body weights attained by week 36 of the experiment generally reflected this same pattern. Weekly food consumption/wastage, as measured by disappearance of food from the feeder, generally showed the converse shelf-level pattern as that shown by body weight gain. Removal of food from feeders was greatest on the top shelf, lowest on the next shelf, and progressively increased with each succeedingly lower shelf. Although it is not clear whether the food removal pattern was related more to food consumption or food wastage, the observation was reproducible. |
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Authors:
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D L Greenman; P Bryant; R L Kodell; W Sheldon |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Laboratory animal science Volume: 33 ISSN: 0023-6764 ISO Abbreviation: Lab. Anim. Sci. Publication Date: 1983 Dec |
Date Detail:
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Created Date: 1984-03-12 Completed Date: 1984-03-12 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 1266503 Medline TA: Lab Anim Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 555-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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2-Acetylaminofluorene Animals Body Weight* Feeding Behavior* Female Housing, Animal* Mice Mice, Inbred BALB C / physiology* Neoplasms, Experimental / chemically induced |
| Chemical | |
Reg. No./Substance:
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53-96-3/2-Acetylaminofluorene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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