Document Detail

Relationship of a large weight loss to long-term weight change among young and middle-aged US women.
MedLine Citation:
PMID:  11477495     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the prevalence of clinically significant weight loss among women and whether this is associated with smaller long-term weight gains.
DESIGN: Six-year follow-up of young and middle-aged women in the Nurses' Health Study II.
SUBJECTS: A total of 47,515 women who did not report a pregnancy, or a diagnosis of cancer or cardiovascular disease any time between 1989 and 1995.
MEASUREMENTS: Self-reported weights in 1989, 1991, 1993 and 1995, dietary intake, physical activity, inactivity, history of weight cycling and smoking.
RESULTS: Between 1989 and 1991, 9% of the women lost > or =5% of their 1989 weight (6% lost 5--9.9% and 3% lost > or =10%). The proportion who lost > or =10% of their weight increased with category of body mass index (BMI, kg/m(2)) from 0.4% among women with a BMI <22 to 9% among women with a BMI > or =30 in 1989. Women who lost > or =5% of their weight between 1989 and 1991 gained more weight between 1991 and 1995 than their peers and the difference increased across categories of BMI in 1989. However, due to their large weight losses, women who lost > or =5% of their weight between 1989 and 1991 overall gained less weight than their peers between 1989 and 1995 (P<0.001). Moreover, women who engaged in 5 or more hours per week of vigorous physical activity gained approximately 0.5 kg less than their inactive peers (P<0.001).
CONCLUSION: Although most women who lost a clinically significant amount of weight regained most of it, they gained less weight over the entire 6 y period than their peers.
A E Field; R R Wing; J E Manson; D L Spiegelman; W C Willett
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity     Volume:  25     ISSN:  -     ISO Abbreviation:  Int. J. Obes. Relat. Metab. Disord.     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-07-30     Completed Date:  2001-12-13     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  9313169     Medline TA:  Int J Obes Relat Metab Disord     Country:  England    
Other Details:
Languages:  eng     Pagination:  1113-21     Citation Subset:  IM    
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MeSH Terms
Body Mass Index
Diet, Reducing
Energy Intake
Follow-Up Studies
Health Surveys
Obesity / epidemiology,  prevention & control
Risk Factors
Weight Gain*
Weight Loss*
Grant Support
CA50385-09/CA/NCI NIH HHS; DK 42600/DK/NIDDK NIH HHS; R29 HL57871-01/HL/NHLBI NIH HHS; S040-11/15//PHS HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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