| Relationship of haptoglobin polymorphism to malaria in the Solomon Islands. | |
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MedLine Citation:
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PMID: 7647399 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Haptoglobin (Hp) polymorphism and its relationship to malaria infections was examined in Solomon Islanders under 25 years of age. The slide positive rate for malaria was 48% (53/111): Plasmodium vivax (Pv) 21 cases, Plasmodium falciparum (Pf) 16 cases and the remaining 16 were a mixture of Pv/Pf/P. malariae. Of 111 subjects examined, 17% (19 subjects) were ahaptoglobinemic (HpO). No association was observed between HpO and parasitemia, gender, anemia, serum insulin-like growth factor-1 (IGF-1) level, blood glucose level and enlargement of the spleen. These results suggest that malaria may not be the major cause of HpO in the people of the Solomon Islands. |
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Authors:
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Y Mizushima; H Kato; H Ohmae; T Tanaka; A Bobogare; A Ishii |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 34 ISSN: 0918-2918 ISO Abbreviation: Intern. Med. Publication Date: 1995 May |
Date Detail:
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Created Date: 1995-09-26 Completed Date: 1995-09-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: JAPAN |
Other Details:
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Languages: eng Pagination: 342-6 Citation Subset: IM |
Affiliation:
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First Department of Internal Medicine, Toyama Medical and Pharmaceutical University. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Animals Antimalarials / therapeutic use Blood Glucose / metabolism Child Child, Preschool Female Haptoglobins / genetics*, metabolism Humans Insulin-Like Growth Factor I / metabolism Malaria / blood*, drug therapy, epidemiology, genetics Male Melanesia / epidemiology Parasitemia / drug therapy, epidemiology, genetics* Phenotype Polymorphism, Genetic* Rural Population |
| Chemical | |
Reg. No./Substance:
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0/Antimalarials; 0/Blood Glucose; 0/Haptoglobins; 67763-96-6/Insulin-Like Growth Factor I |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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