Document Detail

Relationship of cigarette smoking to congenital anomalies and perinatal death. A prospective study.
MedLine Citation:
PMID:  623203     Owner:  NLM     Status:  MEDLINE    
Congenital anomalies caused 3.43 perinatal deaths/1000 births, as reported in a large prospective study. At all gestational ages the mortality rates progressively increased when gravidas smoked more than 10 cigarettes/day. An excessive death rate was also found in males, in offspring of mothers over 39 years of age, and in women of low socioeconomic status. Placentas associated with the malformed infants had an increased frequency of single umbilical arteries and abnormal insertions of fetal membranes and umbilical cords into the placenta.
R L Naeye
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of pathology     Volume:  90     ISSN:  0002-9440     ISO Abbreviation:  Am. J. Pathol.     Publication Date:  1978 Feb 
Date Detail:
Created Date:  1978-03-21     Completed Date:  1978-03-21     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370502     Medline TA:  Am J Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  289-94     Citation Subset:  AIM; IM    
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MeSH Terms
Abnormalities, Drug-Induced / epidemiology*
Fetal Death / chemically induced,  epidemiology*
Gestational Age
Prospective Studies
Socioeconomic Factors
United States

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